The Most proven Stent in the world

Millions of people with angina due to narrowed heart arteries have been helped by the CYPHER^® Stent. It has been the subject of more than 200 clinical trials during the past decade, making it one of the most studied medical devices in history. The CYPHER^® Stent is the most used drug-eluting stent in the world, and has benefited more than 4 million people around the globe.

The CYPHER^® Stent was the first of a generation of heart stents called drug-coated or drug-eluting stents. A major advance over bare-metal stents, the CYPHER^® Stent releases a medication that reduces the risk of re-blockage, or restenosis, in your arteries. Which means you’re a lot less likely to need another procedure. And it also means you’re less likely to suffer from the chest pain and shortness of breath that come with heart disease.

In fact, a key trial showing the efficacy of the CYPHER^® Stent found that up to 5 years after receiving a CYPHER^® Stent, the risk of re-blockage in the treated part of the artery is about 10%, compared to about 26% for an uncoated stent.

How the CYPHER® Stent Works

The CYPHER^® Stent releases a unique anti-rejection-type medicine, sirolimus, into the artery wall over a period of 90 days. The sirolimus helps limit the overgrowth of normal cells while the artery heals. The CYPHER^® Stent has a unique repeat-pattern design that allows the medicine to be distributed more evenly across the treated area. And that helps to keep your arteries open and the blood flowing to your heart, reducing the chance of re-blockage in the treated area.

Thousands of scientific papers have been published about the properties and benefits of sirolimus, the unique medicine in the CYPHER^® Stent.

Confidence in Long-Term Outcomes

The CYPHER^® Stent has been studied longer than any other drug-eluting stent. More than 155,000 patients have been observed in clinical trials over the past decade. And recently published analyses of long-term clinical data reinforce the CYPHER^® Stent’s unsurpassed efficacy in the heart stent category.

Learn how the CYPHER^® Stent procedure is performed